Political relations are good and cooperation with Sao Tome and Principe in international organisations is constructive. There has been a German faculty at the Universidade de São Tomé e Príncipe since 2016 and the number of students learning German has increased significantly. Germans comprise the second largest group of tourists in Sao Tome and Principe, after the Portuguese. Several of Sao Tome and Principe’s former leaders – including former President Manuel Pinto da Costa – studied in the former GDR and have a strong affinity with Germany.

Bilateral relations are looked after via the German Embassy in Libreville, the capital of Gabon. Furthermore, at the start of 2024, Kerstin Schulze was inducted as the new German Honorary Consul based in Sao Tome.

Economic relations between Germany and Sao Tome and Principe have not developed to any significant extent. There are no German firms based in the country.